Magdalena Zernicka-Goetz Group

Mammalian Embryo and Stem Cell Group

MZG lab 2017

Group Head

 

Magdalena Zernicka-Goetz

 

Post-doctoral Scientists

 

Agnieszka Jedrusik

Francesco Antonica

Marta Shahbazi

Ania Hupalowska

Neophytos Christodoulou

Mubeen Goolam

Gianluca Amadei

Matteo Mole

Andy Cox

Back row: John Crang, Andy Cox, Francesco Antonica, Chuen Yan Leung

Middle row: Leah Bury, Monika Bialecka, Magda Zernicka-Goetz, Paula Coelho, Maryna Panamarova

Front row: Aga Jedrusik, Sarah Graham, Mubeen Goolam

Missing: Sarah Harrison, Marta Shahbazi, Meng Zhu,

Ania Hupalowska, Sanna Vuoristo, Neophytos Christodoulou, Shruti Singla, Christos Kyprianou,

Lorenzo Carlo Orietti, Berna Sozen

Photo taken by James Smith

Group head

Magdalena Zernicka-Goetz

Magdalena carried our her Ph.D. at the University of Warsaw, Poland, under supervision of Andrzej Tarkowski. She came to Cambridge in 1995 to join Martin Evans group with the long-term aim of studying the mechanisms of regulative nature of development and spatial patterning in the mouse embryo. In 1997 she was awarded a Senior Research Fellowship from the Lister Institute to start her independent group at the Wellcome Trust/Cancer Research UK Gurdon Institute in Cambridge. In 2001 she became a Wellcome Senior Research Fellow. In 2010, she became a Professor of Mammalian Development and Stem Cell Biology. In 1993 she received a Promising Young Scientist Prize from Foundation for Polish Science, in 2001, Young Investigator Award from EMBO, in 2007 she was elected to EMBO membership and in 2013 she became Fellow of British Academy of Medical Science.

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Postdoctoral Scientist

Agnieszka Jedrusik

Aga joined Magdalena's lab first in 2005 as a summer student and then in 2006 as a PhD student. Aga’s PhD work concentrated on the role of cell polarity and the Cdx2 transcription factor in the mouse blastocyst formation. She established that Cdx2 is provided to the embryo both maternally and zygotically to specify the trophectoderm lineage. Aga defended her PhD in 2011 and became promoted to research associate studying cellular and molecular mechanisms that break embryo symmetry leading to the first cell fate decision that generates pluripotent ICM and the differentiated trophectoderm.

ajj37@cam.ac.uk

Francesco Antonica

Postdoctoral Scientist

Francesco got his Master degree in Industrial Biotechnologies at University of Milan Bicocca in 2008. His work was focused in studying the pathological and molecular mechanisms causing congenital hypogonadism, ovarian insufficiency and congenital hypothyroidism. Afterwards he moved to do the PhD to Brussels at IRIBHM in Sabine Costagliola's lab where he worked in the generation of the first in vitro protocol to differentiate murine pluripotent stem cells into functional thyroid tissue. In 2013 Francesco joined Magda's group to study the regulation of morphogenesis and size in the implanting mouse embryo.

af536@.cam.ac.uk

Marta Shahbazi

Postdoctoral Scientist

Marta completed her BSs in Biology and MSs in Molecular Biomedicine at the University Autonoma of Madrid. She did her PhD at the Spanish National Cancer Research Centre (CNIO) under the supervision of Dr. Mirna Perez-Moreno, working on microtubule binding proteins that regulate cell-cell adhesion in the epidermis. Marta joined Magda's group in 2014 to work on tissue patterning in postimplantation mouse development.

ms2261@cam.ac.uk

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Ania Hupalowska

Postdoctoral Scientist

Science Illustrator

Ania completed her BSc and MSc in Developmental Biology at the University of Warsaw. She did her PhD at the IIMCB in 2012 in the group of prof. Marta Miaczynska, investigating the role of endocytic proteins and intercellular trafficking in nuclear signaling and transcriptional regulation. Having also a BFA degree from graphic design studies, she develops new ways to visualize scientific data. Ania joined Magda's lab in 2014.

akh46@cam.ac.uk

Postdoctoral Scientist

Neophytos Christodoulou

Neophytos Christodoulou did his PhD at the University of Cyprus under the supervision of Dr. Paris Skourides. His work focused on two major subjects, the role of Calpain2 during Xenopus development and the dynamics of actin during Neural Tube Closure morphogenesis. He joined Magdalena's group in 2015 to study the morphogenesis of extraembryonic tissues.

nc480@cam.ac.uk

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Mubeen Goolam

Postdoctoral Scientist

Mubeen obtained his undergraduate and Master's degrees at the University of Cape Town before joining Magda's lab in 2012 as a PhD student. During his PhD studies he was investigating the function of genes that are differentially expressed in the pre-implantation mouse embryo. Mubeen defended his PhD in 2016 and became promoted to research associate continuing studies on early heterogeneity in mouse embryos.

mmg38@cam.ac.uk

Gianluca Amadei

Postdoctoral Scientist

Gianluca completed his PhD at the University of Toronto where he studied the role of RNA-binding proteins in the context of mammalian embryonic brain development. Now, he is studying how RNA-binding proteins regulate very early mammalian embryonic development, from zygote to preimplantation. He is also interested in studying novel ways to model mouse development in post-implantation. Gianluca joined Magdalena's group in 2016.

ga379@cam.ac.uk

Matteo Mole

Postdoctoral Scientist

Matteo completed his MSc in Neuroscience at UCL and did his PhD in Andrew Copp's lab to study the molecular and cellular dynamics underlying neural tube closure. In 2016, he joined Magdalena's group to investigate the role of cell adhesion during post-implantation morphogenesis.

mam238@cam.ac.uk

Andy Cox

Postdoctoral Scientist

Lab Manager

Andy completed his PhD at the University of Southampton, in the Laboratory of Prof. Tom Fleming, and joined Magda’s group in 2013. He studies molecular basis of cell-fate decisions in the pre-implantation embryo.

alc91@cam.ac.uk

Sarah Harrison

PhD Student

Sarah joined the lab as BBSRC DTP PhD student, having just completed an MRes as part of the programme. Her project involves investigation of the self-organising properties of mouse embryonic stem cells in both the presence, and absence of extra-embryonic tissues. Before coming to Cambridge, Sarah read Biological sciences at Merton college, Oxford, graduating in June 2013.

seh201@cam.ac.uk

Meng Zhu

PhD Student

Meng joined  Magda’s lab at the year of 2014 as a PhD student. Before that, she completed her Bachelor’s degree at Tsinghua University, School of Life Sciences. She is studying molecular basis of cell fate decisions in pre-implantation mouse embryo.

mz358@cam.ac.uk

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Christos Kyprianou

PhD Student

Christos joined Magda's lab as a PhD student in 2015. He studied Genetics at the University of Leicester and later obtained a MSc in Clinical Embryology from the University of Oxford. He recently completed a MRes as part of the doctoral training programme funded by BBSRC. His project involves investigating the antero-posterior axis establishment in the mouse embryo and the earliest events of symmetry breaking.

ck464@cam.ac.uk

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Shruti Singla

PhD Student

Shruti completed a rotation in Magda's lab in 2015 under Wellcome Trust 4-year PhD programme. She examined transcriptional patterns in mouse embryonic stem cell rosettes. She will be continuing as a Phd student to investigate mechanisms behind the fate of aneuploidy in mosaic mouse embryos. Before that, she obtained her Bachelor's and Master's degrees from Indian Institute of Technology, Delhi.

ss2223@cam.ac.uk

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Lorenzo Carlo Orietti

PhD Student

Lorenzo completed his BSc in Biotechnology at the University of Milan and a MSc in Molecular Genetics at Imperial College London. After an internship at the IMBA, Vienna he joined Magdalena’s lab as a CTR graduate student in 2015 to study the genetic and epigenetic mechanisms underpinning changes in potency during mouse pre-implantation development.

lco21@cam.ac.uk

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PhD Student

Berna Sozen

Berna compleated her BSc in Biological Sciences and MSc in Reproductive Biology and at Akdeniz University, Turkey. In 2013, she started her PhD in Histology-Embryology at Akdeniz University. Berna was awarded a Research Fellowship to perfom her PhD research and joined Magda's group in 2015 for 1 year period. Her work investigates the role of signaling of the pre- to post-implantation development.

bs568@cam.ac.uk

Rosie Larter

Technician

Rosie joined Magdalena's group in 2016 as a technician for her gap year. She has previously attended Hills Road Sixth Form College and is going on to study Biological Sciences at University in September 2017 .

rjdl3@cam.ac.uk

Former Group Members:

Sanna Vuoristo (Former Post-Doc).

 

Bernhard Strauss (a joint Post-Doc between Magdalena and Jon Pines' lab). Post-Doc with Jon Pines, Cambridge.

 

Paula Coelho (a joint Post-Doc between Magdalena and David Glover's lab). Post-Doc with David Glover, Cambridge.

 

Sarah Graham (Former Post-Doc). Medical Writer with Oxford PharmaGenesis.

 

Gaelle Recher (Former Post-Doc). Post-Doc at the University of Bordeaux.

 

Ivan Bedzhov (Former Post-Doc). Principal Investigator at Max Planck Institute for Molecular Biomedicine, Munster, Germany.

 

Monika Bialecka (Former Post-Doc). Post-Doc at  the University of Leiden, Netherlands.

 

Chuen Yan Leung (Former PhD Student). Post Doc with Kenneth Chien, Integrated Cardio Metabolic Center, Karolinska Institute.

 

Maryna Panamarova (Former PhD Student). Post-Doc at King's College London.

 

Maria Skamagki (Former PhD Student). Post-Doc with Kitai Kim, Sloan-Kettering Institute. New York.

 

Anna Ajduk (Former Post-Doc). Associate Professor at Warsaw University.

 

Samantha Morris (Former Post-Doc). Post-Doc with George Daley, Harvard, Children's Hospital Boston.

 

Roy Teo (Former PhD Student).

Seema Grewal (Former Post-Doc). Reviews editor at Development.

 

Alex Bruce (Former Post-Doc). Group Leader. University of South Bohemia. Czech Republic.

 

Emlyn Parfitt (Former PhD Student). Post-Doc, with Micheal Shen, Columbia University, NYC.

 

Rui Martins (Former Post-Doc). Post-Doc, London.

 

Qiang Wu (Former Post-Doc). Assistant Professor, Singapore.

 

Maria Elena Torres-Padilla (Former Post-Doc). Chargée de Recherche, Strasbourg, France.

 

Lucy Richardson (Former PhD Student). Scientist in IVF clinic

 

Joanna Grabarek (Former Post-Doc). Post-Doc with Dr. Berenicka Plusa

 

Lee Carpenter. Senior Scientist, Stem Cells and Immunotherapies, NHS Blood and Transplant, John Radcliffe Hospital, Oxford, UK. Former post-doctoral fellow.

 

Stephen Frankenberg. Post-doc with Dr. Claire Chazaud at Faculté de Médecine, Clermont-Ferrand, France. Former post-doctoral fellow.

 

Dionne Gray. Research assistant at the Department of Anatomy, University of Cambridge. Former research assistant.

 

Seiki Haraguchi. Senior Scientist at Chiba Cancer Center Research Institute, Chiba, Japan. Former post-doctoral fellow.

 

Karin Lyke-Anderesen. Adjunkt, Assistant Professor, Department of Molecular Biology, Aarhus University, Denmark. Former post-doctoral fellow.

 

Sigolene Meilhac. Chargée de Recherche à l’Institut Pasteur, Paris, France. Former post-doctoral fellow.

 

Daniel Mesnard. Post-doc with Dr. Daniel Constam, ISREC, Lausanne, Switzerland. Former PhD student obtained his Ph.D. thesis in 2005 under the direction of M. Zernicka-Goetz.

 

Catherine Moore. Post-doc with Prof. Phil Ingham at University of Sheffield, United Kingdom. Former graduate student, obtained her Ph.D. thesis in 2005 under the direction of M. Zernicka-Goetz.

 

Jie Na. Research Fellow, Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, United Kingdom. Former post-doctoral fellow.

 

Karolina Piotrowska-Nitsche. Post-doc with Prof. Anthony Chan, Yerkes National Primates Research Center, Department of Human Genetics, Emory University, Atlanta, USA. Former post-doctoral fellow.

 

Berenika Plusa. Former post-doctoral fellow, received an independent fellowship to set up a group in Manchester

 

Miguel Soares. Post-doc with Dr. Anne Fergunson-Smith, Department of Anatomy, University of Cambridge. Former post-doctoral fellow.

 

Roberta Weber. London, United Kingdom. Former research assistant.

 

Florence Wianny. Chargée de Recherche INSERM atDepartment of Stem Cells and Cortical Development, Lyon, France. Former post-doctoral fellow.

 

Krzysztof Wicher. Scientist at MedImmune, Cambridge, UK. Former post-doctoral fellow.

 

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