Magdalena Zernicka-Goetz Group

Mammalian Embryo and Stem Cell Group

Meet the lab


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Early embryos kept in check or how embryos coordinate the exit from pluripotency?


Pluripotency regulates mouse and human embryonic morphogenesis: cells that are in an unrestricted naive pluripotent state (marked by the expression of Nanog in yellow) fail to undergo proper morphogenesis and form the amniotic cavity (left structure). Loss of naive pluripotency (marked by the lack of Nanog expression) directs morphogenesis and amniotic cavity formation (right structure).

Fot. Marta Shahbazi

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