Meet the lab
Dr. Agnieszka Jedrusik
Dr. Francesco Antonica
Lorenzo Carlo Orietti
Dr. Neophytos Christodoulou
Dr. Andy Cox
Dr. Gianluca Amadei
Dr. Matteo Mole
Dr. Ania Hupalowska
Science Illustrator/Postdoctoral Scientist
Dr. Marta Shahbazi
Best lab citizen:
Early embryos kept in check or how embryos coordinate the exit from pluripotency?
Pluripotency regulates mouse and human embryonic morphogenesis: cells that are in an unrestricted naive pluripotent state (marked by the expression of Nanog in yellow) fail to undergo proper morphogenesis and form the amniotic cavity (left structure). Loss of naive pluripotency (marked by the lack of Nanog expression) directs morphogenesis and amniotic cavity formation (right structure).
Fot. Marta Shahbazi
The long-term goal of our work is to understand the development of cell lineages and patterning in the early mammalian embryo. Find out more...
Imaging a human embryo in the absence of maternal tissues.
Shahbazi M et al. 2016 Nat Cell Biol
The fate of aneuploid cells in mouse embryo
Bolton H et al. 2016 Nat Commun
Early heterogeneity in
4-cell mouse embryos
Goolam et al. 2016 Cell
Cdx2 or not Cdx2..?
Jedrusik A et al. 2014 Dev Biol